Methoxytriphenylmethane

Methoxytriphenylmethane

SCHEMBL9103

COC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.48

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.48
CYP19A1 P11511 1/20 0.47
CES1 P23141 1/20 0.45
KCNN4 O15554 5/20 0.44
KIF11 P52732 1/20 0.44
ALDH1A1 P00352 3/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 2/20 0.41
CA4 P22748 1/20 0.41
TAAR1 Q96RJ0 1/20 0.39
CYP2B6 P20813 1/20 0.38
ESR1 P03372 1/20 0.37
CYP3A4 P08684 1/20 0.37
ESR2 Q92731 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methoxytriphenylmethane SCHEMBL27882817 0.97 MAPK1 (0.46) MAPK1CYP19A1CES1KCNN4KIF11
SCHEMBL8785784 0.88 CYP19A1 (0.44) MAPK1CYP19A1CES1KCNN4KIF11
SCHEMBL15960119 0.86 CYP19A1 (0.43) MAPK1CYP19A1CES1KCNN4KIF11
SCHEMBL8784660 0.86 CA4 (0.54) CYP19A1CES1KIF11CA4
SCHEMBL774134 0.86 CA4 (0.54) CYP19A1CES1KIF11CA4
Hydrochloric Acid SCHEMBL30389842 0.84 CA4 (0.52) CYP19A1CES1KIF11ALDH1A1CA4
Bromide SCHEMBL31164184 0.84 CA4 (0.52) CYP19A1CES1KIF11CA4
SCHEMBL11091542 0.81 CYP19A1 (0.37) MAPK1CYP19A1CES1KCNN4KIF11
SCHEMBL5200151 0.81 ALDH1A1 (0.48) MAPK1CYP19A1CES1KCNN4KIF11
SCHEMBL8785612 0.79 ACHE (0.45) CYP19A1KIF11CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13253 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118345073-A GalNAc derivative 詹森生物制药有限公司 2024-07-16 CN claimed
US-12030907-B2 Modified nucleoside phosphoramidites Janssen Biopharma, Inc. (US) 2024-07-09 US claimed
US-20240218365-A1 FORMULATION OF AN ANTISENSE OLIGOMER CONJUGATE THE PROGERIA RESEARCH FOUNDATION, INC. 2024-07-04 US claimed
EP-4392558-A1 ANTISENSE OLIGONUCLEOTIDES HAVING ONE OR MORE ABASIC UNITS Sarepta Therapeutics, Inc. (US) 2024-07-03 EP claimed
EP-4387676-A2 DELIVERY OF ANITSENSE OLIGOMERS BY MIRROR IMAGE PEPTIDES Sarepta Therapeutics, Inc. (US) 2024-06-26 EP claimed
CN-115038790-B Synthesis of 3' -RNA oligonucleotides 阿尔尼拉姆医药品有限公司 2024-06-21 CN claimed
CN-118184532-A Amino acid having functional group capable of forming intramolecular hydrogen bond, peptide compound containing the amino acid, and process for producing the same 中外制药株式会社 2024-06-14 CN claimed
EP-4380624-A1 MULTIVALENT LIGAND CLUSTERS WITH DIAMINE SCAFFOLD FOR TARGETED DELIVERY OF THERAPEUTIC AGENTS Shanghai Argo Biopharmaceutical Co., Ltd. (CN) 2024-06-12 EP claimed
CN-112384520-B Method for producing oligonucleotide compound 日本新药株式会社 2024-06-11 CN claimed
CN-118146284-A GalNAc compound, oligonucleotide conjugate and preparation method thereof 北京悦康科创医药科技股份有限公司 2024-06-07 CN claimed
EP-0177382-A1 Mixed probe and its application, its precursor, its preparation and derivatives containing a modified base for this preparation INSTITUT PASTEUR (FR) 1986-04-09 EP claimed
EP-0135587-A4 DEFINED SEQUENCE SINGLE STRAND OLIGONUCLEOTIDES INCORPORATING REPORTER GROUPS, PROCESS FOR THE CHEMICAL SYNTHESIS THEREOF, AND NUCLEOSIDES USEFUL IN SUCH SYNTHESIS. MOLECULAR BIOSYSTEMS INC (US) 1986-04-02 EP claimed
EP-0135587-A1 DEFINED SEQUENCE SINGLE STRAND OLIGONUCLEOTIDES INCORPORATING REPORTER GROUPS, PROCESS FOR THE CHEMICAL SYNTHESIS THEREOF, AND NUCLEOSIDES USEFUL IN SUCH SYNTHESIS. MOLECULAR BIOSYSTEMS INC (US) 1985-04-03 EP claimed
EP-0121635-A1 3',5',-Diarabinosides, their preparation and their therapeutical application SYNTHELABO (FR) 1984-10-17 EP claimed
EP-0121112-A1 2'-Deoxy-3-phosphonylmethyl nucleosides and method for their preparation Gesellschaft für Biotechnologische Forschung mbH (GBF) (DE) 1984-10-10 EP claimed
WO-1984003285-A1 DEFINED SEQUENCE SINGLE STRAND OLIGONUCLEOTIDES INCORPORATING REPORTER GROUPS, PROCESS FOR THE CHEMICAL SYNTHESIS THEREOF, AND NUCLEOSIDES USEFUL IN SUCH SYNTHESIS MOLECULAR BIOSYSTEMS INC (US) 1984-08-30 WO claimed
US-4458066-A BOUND TO INORGANIC SUPPORT UNIVERSITY PATENTS, INC. (US) 1984-07-03 US claimed
EP-0058563-A1 Lyophilized phosphorylated nucleosides ens BIO LOGICALS INC. (CA) 1982-08-25 EP claimed
EP-0049072-A1 Guanine compounds and their use for the preparation of anti-viral agents SYNTEX (U.S.A.) INC. (US) 1982-04-07 EP claimed
EP-0035719-A2 Process for producing modified inorganic polymers, their use in producing polynucleotides, and a reagent useful in these processes UNIVERSITY PATENTS, INC. (US) 1981-09-16 EP claimed