Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.40 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30230864 | 0.81 | NOS3 (0.42) | PIK3CDLTA4HMAP4K4CYP1A2KCNH2 | |
| SCHEMBL31306313 | 0.81 | BPTF (0.42) | AKT1USP2TP53MAPK1MEN1 | |
| SCHEMBL30231000 | 0.80 | PIK3CD (0.49) | PIK3CDMAP4K4ATMNOS3NOS2 | |
| SCHEMBL30231060 | 0.78 | PIK3CD (0.45) | PIK3CDMAP4K4ATMNOS3NOS2 | |
| SCHEMBL13683160 | 0.74 | PIK3CD (0.46) | PIK3CDLTA4HMAP4K4CYP1A2KCNH2 | |
| SCHEMBL30231058 | 0.70 | ATM (0.42) | PIK3CDLTA4HMAP4K4ATMNOS3 | |
| SCHEMBL30231174 | 0.70 | ATM (0.48) | PIK3CDLTA4HMAP4K4CYP1A2KCNH2 | |
| SCHEMBL11908832 | 0.70 | PDE2A (0.48) | PIK3CDCYP1A2ATMMEN1KMT2A | |
| SCHEMBL19140288 | 0.69 | PIK3CD (0.41) | PIK3CDLTA4HMAP4K4CYP1A2KCNH2 | |
| SCHEMBL17796572 | 0.69 | CYP1A2 (0.47) | PIK3CDLTA4HMAP4K4CYP1A2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116568676-A | IL-17A modulators | 赛诺菲 | 2023-08-08 | — | — | CN | disclosed |
| CN-116547275-A | IL-17A modulators | 赛诺菲 | 2023-08-04 | — | — | CN | disclosed |
| EP-4157827-A1 | IL-17A MODULATORS | SANOFI (FR) | 2023-04-05 | — | — | EP | disclosed |