SCHEMBL30230992

SCHEMBL30230992

BrC1c2ccccc2-c2ccccc21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.46
HTR2A P28223 2/20 0.46
HDAC3 O15379 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
HDAC9 Q9UKV0 1/20 0.39
HDAC5 Q9UQL6 1/20 0.39
NCOR2 Q9Y618 1/20 0.39
POLB P06746 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
ACHE P22303 3/20 0.37
BCHE P06276 2/20 0.37
CHRM2 P08172 1/20 0.37
HTR1A P08908 1/20 0.37
ADRA2A P08913 1/20 0.37
CHRM1 P11229 1/20 0.37
DRD1 P21728 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL708297 1.00 GPR3 (0.46) GPR3HTR2AHDAC3HDAC4HDAC7
Bromide SCHEMBL29090090 0.97 GPR3 (0.44) GPR3HTR2AHDAC3HDAC4HDAC7
SCHEMBL6902840 0.84 MEN1 (0.52) NCOR2POLBCYP1A2BCHEKMT2A
SCHEMBL31124667 0.83 MEN1 (0.35) GPR3HTR2AKMT2AMEN1
SCHEMBL6055957 0.82 GPR3 (0.34) GPR3HTR2AHDAC3HDAC4HDAC7
SCHEMBL2672974 0.82 CYP1A2 (0.46) GPR3HTR2AHDAC3HDAC4HDAC7
SCHEMBL3263053 0.81 GPR3 (0.46) GPR3HTR2AHDAC3HDAC4HDAC7
SCHEMBL31318355 0.80 GPR3 (0.46) GPR3HTR2ACHRM2HTR1AADRA2A
SCHEMBL27811287 0.80 GPR3 (0.46) GPR3HTR2ACYP1A2HTR1ASLC6A2
SCHEMBL27818578 0.80 PPIA (0.43) GPR3POLBCYP1A2HTR1ASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12420321-B1 Method for degrading halogenated polycyclic aromatic hydrocarbons in soil by using cryptomelane NANJING AGRICULTURAL UNIVERSITY (CN) 2025-09-23 US claimed
US-12420321-B1 Method for degrading halogenated polycyclic aromatic hydrocarbons in soil by using cryptomelane NANJING AGRICULTURAL UNIVERSITY (CN) 2025-09-23 US disclosed
EP-4157827-A1 IL-17A MODULATORS SANOFI (FR) 2023-04-05 EP disclosed
EP-4153561-A2 9H-FLUOREN DERIVATES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS UNIWERSYTET JAGIELLONSKI (PL) 2023-03-29 EP disclosed