Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 16/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 3/20 | 1.00 |
| ▸ | TSHR | P16473 | 3/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 2/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 2/20 | 1.00 |
| ▸ | THPO | P40225 | 2/20 | 1.00 |
| ▸ | MTOR | P42345 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.81 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.81 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.80 |
| ▸ | LMNA | P02545 | 1/20 | 0.80 |
| ▸ | DRD2 | P14416 | 9/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2970804 | 1.00 | DRD1 (1.00) | DRD1KDM4EMAPTPMP22TSHR | |
| SCHEMBL30026797 | 1.00 | DRD1 (1.00) | DRD1KDM4EMAPTPMP22TSHR | |
| Bromide SCHEMBL29634914 | 0.99 | DRD1 (1.00) | DRD1KDM4EMAPTPMP22TSHR | |
| Bromide SCHEMBL12610614 | 0.99 | DRD1 (1.00) | DRD1KDM4EMAPTPMP22TSHR | |
| SCHEMBL14510734 | 0.90 | DRD1 (0.81) | DRD1KDM4EMAPTPMP22TSHR | |
| SCHEMBL7323497 | 0.88 | DRD1 (1.00) | DRD1KDM4EMAPTPMP22TSHR | |
| Bromide SCHEMBL29634894 | 0.87 | DRD1 (1.00) | DRD1KDM4EMAPTPMP22TSHR | |
| Bromide SCHEMBL7320300 | 0.87 | DRD1 (1.00) | DRD1KDM4EMAPTPMP22TSHR | |
| SCHEMBL34464664 | 0.87 | DRD1 (0.80) | DRD1KDM4EMAPTPMP22TSHR | |
| SCHEMBL14495044 | 0.84 | DRD1 (0.72) | DRD1KDM4EMAPTPMP22TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023101866-A1 | FENFLURAMINE FOR TREATMENT OF CONDITIONS ASSOCIATED WITH SPREADING DEPOLARIZATION | ZOGENIX INTERNATIONAL LIMITED (GB) | 2023-06-08 | — | — | WO | disclosed |
| WO-2023006412-A1 | SIGMA-1 RECEPTOR ACTIVATOR FOR USE IN THE TREATMENT OF A PATHOLOGY ASSOCIATED WITH WFS1 MUTATION | UNIVERSITÉ DE MONTPELLIER (FR) | 2023-02-02 | — | — | WO | disclosed |