Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 15/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.72 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.72 |
| ▸ | TSHR | P16473 | 3/20 | 0.72 |
| ▸ | THPO | P40225 | 3/20 | 0.72 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.72 |
| ▸ | MTOR | P42345 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | DRD2 | P14416 | 8/20 | 0.69 |
| ▸ | HTR2A | P28223 | 5/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14510734 | 0.87 | DRD1 (0.81) | DRD1KDM4EHSD17B10MAPTPMP22 | |
| SCHEMBL2970804 | 0.84 | DRD1 (1.00) | DRD1KDM4EHSD17B10MAPTPMP22 | |
| SCHEMBL30231809 | 0.84 | DRD1 (1.00) | DRD1KDM4EHSD17B10MAPTPMP22 | |
| SCHEMBL30026797 | 0.84 | DRD1 (1.00) | DRD1KDM4EHSD17B10MAPTPMP22 | |
| Bromide SCHEMBL29634914 | 0.83 | DRD1 (1.00) | DRD1KDM4EHSD17B10MAPTPMP22 | |
| Bromide SCHEMBL12610614 | 0.83 | DRD1 (1.00) | DRD1KDM4EHSD17B10MAPTPMP22 | |
| SCHEMBL14495040 | 0.81 | DRD1 (0.52) | DRD1KDM4EHSD17B10MAPTPMP22 | |
| SCHEMBL14495025 | 0.80 | DRD1 (0.70) | DRD1KDM4EHSD17B10MAPTPMP22 | |
| Bromide SCHEMBL11542259 | 0.75 | DRD1 (0.74) | DRD1KDM4EHSD17B10MAPTPMP22 | |
| SCHEMBL11256942 | 0.75 | DRD1 (0.76) | DRD1KDM4EHSD17B10MAPTPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070142399-A1 | Dual function drugs and uses thereof | PSYCHIATRIC GENOMICS, INC. (US) | 2007-06-21 | — | — | US | disclosed |
| US-20070142399-A1 | Dual function drugs and uses thereof | PSYCHIATRIC GENOMICS, INC. (US) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142399-A1 | Dual function drugs and uses thereof | COMT, DRD2, SLC6A3 | DRD1 6/4885KDM4E 3362/4885HSD17B10 624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.