Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 18/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 14/20 | 0.63 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3022462 | 0.99 | ADORA3 (0.62) | ADORA3ADORA1ADORA2A | |
| SCHEMBL3022869 | 0.91 | ADORA3 (0.54) | ADORA3ADORA1ADORA2A | |
| SCHEMBL3022866 | 0.91 | ADORA3 (0.54) | ADORA3ADORA1ADORA2A | |
| SCHEMBL3022452 | 0.87 | ADORA3 (0.56) | ADORA3ADORA1ADORA2A | |
| Hydrochloric Acid SCHEMBL3016044 | 0.85 | ADORA3 (0.67) | ADORA3ADORA1ADORA2A | |
| SCHEMBL3026658 | 0.85 | ADORA3 (0.61) | ADORA3ADORA1ADORA2A | |
| SCHEMBL3011335 | 0.83 | ADORA3 (0.52) | ADORA3ADORA1ADORA2A | |
| SCHEMBL3011474 | 0.82 | ADORA3 (0.49) | ADORA3ADORA1ADORA2A | |
| SCHEMBL3011264 | 0.82 | ADORA3 (0.49) | ADORA3ADORA1ADORA2A | |
| SCHEMBL3011253 | 0.82 | ADORA3 (0.49) | ADORA3ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197914-A1 | Purine Derivatives as Adenosine Al Receptor Ligands | NOVARTIS AG (CH) | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197914-A1 | Purine Derivatives as Adenosine Al Receptor Ligands | ADORA2A, ADORA1, ADORA3 | ADORA3 3/4885ADORA1 2/4885ADORA2A 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.