Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30686432 | 0.88 | HCAR3 (0.43) | LMNAFGFR1F10ALDH1A1F2 | |
| SCHEMBL30686444 | 0.84 | BRD4 (0.48) | BRD4RAB9AGAAKDM4EPOLB | |
| SCHEMBL31202855 | 0.83 | BRD4 (0.46) | BRD4RAB9AGAAKDM4EPOLB | |
| SCHEMBL17263019 | 0.81 | KDM4E (0.51) | BRD4RAB9AKDM4EPOLBMAPT | |
| SCHEMBL29559350 | 0.81 | BRD4 (0.47) | BRD4RAB9AKDM4EPOLBMAPT | |
| SCHEMBL30233119 | 0.78 | BRD4 (0.49) | BRD4RAB9AKDM4EPOLBMAPT | |
| SCHEMBL30233099 | 0.77 | CYP11B1 (0.55) | LMNASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL17807884 | 0.76 | BRD4 (0.59) | BRD4SMN1; SMN2FGFR1ALDH1A1CNR1 | |
| SCHEMBL30202437 | 0.76 | BRD4 (0.59) | BRD4SMN1; SMN2FGFR1ALDH1A1CNR1 | |
| SCHEMBL30232676 | 0.74 | BRD4 (0.46) | BRD4RAB9AKDM4EPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117242067-B | Novel aryl ether substituted heterocycles as GLP1R agonists | 杭州德睿智药科技有限公司 | 2025-03-25 | — | — | CN | disclosed |
| CN-117242067-A | Novel aryl ether substituted heterocycles as GLP1R agonists | 杭州德睿智药科技有限公司 | 2023-12-15 | — | — | CN | disclosed |
| WO-2023029380-A1 | NOVEL ARYL ETHER SUBSTITUTED HETEROCYCLIC COMPOUND AS GLP1R AGONIST | 杭州德睿智药科技有限公司 | 2023-03-09 | — | — | WO | disclosed |