Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 17/20 | 0.40 |
| ▸ | LCP2 | Q13094 | 1/20 | 0.38 |
| ▸ | RPS6KA2 | Q15349 | 2/20 | 0.38 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28975036 | 0.91 | MAP4K1 (0.38) | MAP4K1LCP2RPS6KA2PRKD2 | |
| SCHEMBL29261261 | 0.91 | MAP4K1 (0.38) | MAP4K1LCP2RPS6KA2PRKD2 | |
| SCHEMBL25099884 | 0.86 | MAP4K1 (0.51) | MAP4K1LCP2RPS6KA2PRKD2 | |
| SCHEMBL29261252 | 0.86 | MAP4K1 (0.51) | MAP4K1LCP2RPS6KA2PRKD2 | |
| SCHEMBL29261224 | 0.86 | MAP4K1 (0.42) | MAP4K1 | |
| SCHEMBL25100255 | 0.86 | MAP4K1 (0.42) | MAP4K1 | |
| SCHEMBL23987780 | 0.82 | MAP4K1 (0.43) | MAP4K1LCP2 | |
| SCHEMBL29261270 | 0.82 | MAP4K1 (0.42) | MAP4K1ADORA2AADORA1 | |
| SCHEMBL25100253 | 0.81 | ADORA2A (0.38) | MAP4K1ADORA2AADORA1 | |
| SCHEMBL29261274 | 0.81 | ADORA2A (0.38) | MAP4K1ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023030478-A1 | PYRIDOLACTAM DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江海正药业股份有限公司 | 2023-03-09 | — | — | WO | disclosed |