Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 19/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29261224 | 1.00 | MAP4K1 (0.42) | MAP4K1KDM4EMAPTL3MBTL1 | |
| SCHEMBL23987780 | 0.90 | MAP4K1 (0.43) | MAP4K1 | |
| SCHEMBL25099884 | 0.87 | MAP4K1 (0.51) | MAP4K1 | |
| SCHEMBL29261252 | 0.87 | MAP4K1 (0.51) | MAP4K1 | |
| SCHEMBL30233262 | 0.86 | MAP4K1 (0.40) | MAP4K1 | |
| SCHEMBL30233218 | 0.85 | MAP4K1 (0.39) | MAP4K1 | |
| SCHEMBL25099941 | 0.84 | PIK3C3 (0.45) | — | |
| SCHEMBL29261342 | 0.84 | PIK3C3 (0.45) | — | |
| SCHEMBL29261270 | 0.84 | MAP4K1 (0.42) | MAP4K1 | |
| SCHEMBL22011643 | 0.82 | KDM4E (0.39) | MAP4K1KDM4EMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118103369-A | Pyridolactam derivatives, preparation method and application thereof | 浙江海正药业股份有限公司 | 2024-05-28 | — | — | CN | disclosed |
| WO-2023030478-A1 | PYRIDOLACTAM DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江海正药业股份有限公司 | 2023-03-09 | — | — | WO | disclosed |
| WO-2023030478-A1 | PYRIDOLACTAM DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江海正药业股份有限公司 | 2023-03-09 | — | — | WO | disclosed |