Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.46 |
| ▸ | KDM4A | O75164 | 8/20 | 0.46 |
| ▸ | KDM5C | P41229 | 7/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 7/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.46 |
| ▸ | KDM3A | Q9Y4C1 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | KDM6B | O15054 | 4/20 | 0.46 |
| ▸ | KDM5A | P29375 | 4/20 | 0.46 |
| ▸ | TET3 | O43151 | 1/20 | 0.46 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ASPH | Q12797 | 1/20 | 0.46 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.46 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.46 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.46 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.46 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.46 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29272445 | 1.00 | KDM4C (0.46) | KDM4CKDM4AKDM5CKDM5BKDM2A | |
| SCHEMBL16094504 | 0.82 | KDM4C (0.53) | KDM4CKDM4AKDM5CKDM5BKDM2A | |
| SCHEMBL4782749 | 0.82 | KDM4C (0.53) | KDM4CKDM4AKDM5CKDM5BKDM2A | |
| SCHEMBL30504055 | 0.82 | KDM4C (0.53) | KDM4CKDM4AKDM5CKDM5BKDM2A | |
| SCHEMBL29272126 | 0.79 | JMJD6 (0.49) | KDM4CKDM5CKDM5BKDM4EKDM5A | |
| SCHEMBL30379389 | 0.79 | KDM4C (0.50) | KDM4CKDM4AKDM5CKDM5BKDM2A | |
| SCHEMBL26087368 | 0.79 | KDM4C (0.50) | KDM4CKDM4AKDM5CKDM5BKDM2A | |
| SCHEMBL16055561 | 0.79 | KMO (0.53) | KDM4CKDM4AKDM5CKDM5BKDM2A | |
| SCHEMBL16121446 | 0.78 | KDM4C (0.49) | KDM4CKDM4AKDM5CKDM5BKDM2A | |
| Nitrous Acid SCHEMBL29117354 | 0.76 | KDM4C (0.47) | KDM4CKDM4AKDM5CKDM5BKDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4399210-A1 | 6-AZA-QUINOLINE DERIVATIVES AND RELATED USES | Black Diamond Therapeutics, Inc. (US) | 2024-07-17 | — | — | EP | disclosed |
| CN-118159537-A | 6-Aza-quinoline derivatives and related uses | 黑钻治疗公司 | 2024-06-07 | — | — | CN | disclosed |
| WO-2023039505-A1 | 6-AZA-QUINOLINE DERIVATIVES AND RELATED USES | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2023-03-16 | — | — | WO | disclosed |