Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSF1 | Q00613 | 14/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30237248 | 0.77 | HSF1 (0.56) | HSF1ATMPOLBTSHR | |
| SCHEMBL30237520 | 0.75 | HSF1 (0.54) | HSF1ATMCYP2D6CYP2C19TSHR | |
| Hydrochloric Acid SCHEMBL3068296 | 0.75 | HSF1 (0.57) | HSF1ATMCYP2D6CYP2C19KDM4E | |
| Hydrochloric Acid SCHEMBL3068294 | 0.75 | HSF1 (0.57) | HSF1ATMCYP2D6CYP2C19KDM4E | |
| SCHEMBL30237259 | 0.73 | HSF1 (0.56) | HSF1ATMCYP2D6CYP2C19POLB | |
| SCHEMBL3060503 | 0.73 | HSF1 (0.60) | HSF1ATMCYP2D6CYP2C19POLB | |
| SCHEMBL3060495 | 0.73 | HSF1 (0.60) | HSF1ATMCYP2D6CYP2C19POLB | |
| SCHEMBL9426850 | 0.73 | HSF1 (0.60) | HSF1ATMCYP2D6CYP2C19KDM4E | |
| SCHEMBL9426852 | 0.73 | HSF1 (0.60) | HSF1ATMCYP2D6CYP2C19KDM4E | |
| SCHEMBL6009202 | 0.72 | HSF1 (0.65) | HSF1CYP2D6KDM4ETSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4408533-A1 | OXIMES AND THEIR USE IN TREATMENT OF GBA-RELATED DISEASES | Zevra Denmark A/S (DK) | 2024-08-07 | — | — | EP | disclosed |
| WO-2023053008-A1 | OXIMES AND THEIR USE IN TREATMENT OF GBA-RELATED DISEASES | KEMPHARM DENMARK A/S (DK) | 2023-04-06 | — | — | WO | disclosed |