SCHEMBL30237259

SCHEMBL30237259

Cc1cc(C(Cl)=NOCC(O)CN2CCCCC2)on1

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HSF1 Q00613 15/20 0.56
POLB P06746 1/20 0.42
TSHR P16473 1/20 0.41
ATM Q13315 1/20 0.40
ACE2 Q9BYF1 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3060651 0.75 HSF1 (0.57) HSF1TSHRATMCYP2D6CYP2C19
Hydrochloric Acid SCHEMBL3060654 0.75 HSF1 (0.57) HSF1TSHRATMCYP2D6CYP2C19
SCHEMBL30237248 0.75 HSF1 (0.56) HSF1POLBTSHRATMACE2
SCHEMBL30237178 0.73 HSF1 (0.55) HSF1POLBTSHRATMCYP2D6
SCHEMBL3060503 0.73 HSF1 (0.60) HSF1POLBTSHRATMACE2
SCHEMBL3060495 0.73 HSF1 (0.60) HSF1POLBTSHRATMACE2
SCHEMBL6009203 0.72 HSF1 (0.65) HSF1TSHRCYP2D6
SCHEMBL6009202 0.72 HSF1 (0.65) HSF1TSHRCYP2D6
Hydrochloric Acid SCHEMBL3076170 0.72 HSF1 (0.64) HSF1TSHRCYP2D6CYP2C19
Hydrochloric Acid SCHEMBL3076169 0.72 HSF1 (0.64) HSF1TSHRCYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4408533-A1 OXIMES AND THEIR USE IN TREATMENT OF GBA-RELATED DISEASES Zevra Denmark A/S (DK) 2024-08-07 EP disclosed
WO-2023053008-A1 OXIMES AND THEIR USE IN TREATMENT OF GBA-RELATED DISEASES KEMPHARM DENMARK A/S (DK) 2023-04-06 WO disclosed