SCHEMBL30239103

SCHEMBL30239103

CCCCCC(=O)Nc1ccn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)n1

nearest known ligand 0.70

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.50
ADRB1 P08588 1/20 0.47
DNMT1 P26358 1/20 0.47
TK2 O00142 1/20 0.44
ABL1 P00519 1/20 0.43
RIN1 Q13671 1/20 0.43
TSPO P30536 1/20 0.43
POLA1 P09884 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2728382 0.99 POLB (0.49) POLBADRB1DNMT1TK2ABL1
SCHEMBL17304819 0.94 POLB (0.46) POLBADRB1DNMT1
SCHEMBL38653997 0.91 POLB (0.45) POLBADRB1DNMT1ABL1RIN1
SCHEMBL30238601 0.87 PLA2G1B (0.52) POLB
SCHEMBL17522659 0.86 POLB (0.47) POLBADRB1DNMT1ABL1RIN1
SCHEMBL16281862 0.86 POLB (0.47) POLBADRB1DNMT1ABL1RIN1
SCHEMBL21011276 0.86 POLB (0.56) POLBADRB1DNMT1TK2ABL1
SCHEMBL22942033 0.86 POLB (0.56) POLBADRB1DNMT1TK2ABL1
SCHEMBL3627002 0.86 POLB (0.56) POLBADRB1DNMT1TK2ABL1
SCHEMBL3626999 0.86 POLB (0.56) POLBADRB1DNMT1TK2ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3681897-B1 N4-MODIFIED CYTIDINE NUCLEOTIDES AND THEIR USE UNIV VILNIUS (LT) 2025-05-14 EP disclosed
US-11584772-B2 N4-modified cytidine nucleotides and their use VILNIUS UNIVERSITY (LT) 2023-02-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11584772-B2 N4-modified cytidine nucleotides and their use PNP, RNGTT, ADA POLB 100/4885ADRB1 3856/4885DNMT1 153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.