SCHEMBL30239199

SCHEMBL30239199

C[C@H](N)c1csc2ccccc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.55
CYP2A6 P11509 3/20 0.46
MAPT P10636 1/20 0.46
SLC6A2 P23975 3/20 0.42
SLC6A4 P31645 2/20 0.42
SLC6A3 Q01959 1/20 0.42
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1105793 1.00 ALOX5 (0.55) ALOX5CYP2A6MAPTSLC6A2SLC6A4
SCHEMBL141272 1.00 ALOX5 (0.55) ALOX5CYP2A6MAPTSLC6A2SLC6A4
Hydrochloric Acid SCHEMBL1096731 0.98 ALOX5 (0.54) ALOX5CYP2A6MAPTSLC6A2SLC6A4
Hydrochloric Acid SCHEMBL10460821 0.98 ALOX5 (0.54) ALOX5CYP2A6MAPTSLC6A2SLC6A4
SCHEMBL717441 0.83 ALOX5 (0.54) ALOX5CYP2A6MAPTSLC6A2SLC6A4
SCHEMBL25462183 0.80 ALOX5 (0.51) ALOX5CYP2A6MAPTSLC6A2SLC6A4
SCHEMBL2977121 0.80 ALOX5 (0.51) ALOX5CYP2A6MAPTSLC6A2SLC6A4
SCHEMBL1095514 0.80 ALOX5 (0.55) ALOX5CYP2A6MAPTSLC6A2SLC6A4
SCHEMBL2967148 0.80 ALOX5 (0.55) ALOX5CYP2A6MAPTSLC6A2SLC6A4
SCHEMBL24406257 0.80 ALOX5 (0.55) ALOX5CYP2A6MAPTSLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111518166-B Peptidomimetics compound or pharmaceutically acceptable salt thereof, and preparation method and application thereof 中国药科大学 2023-01-31 CN claimed
CN-111518166-B Peptidomimetics compound or pharmaceutically acceptable salt thereof, and preparation method and application thereof 中国药科大学 2023-01-31 CN disclosed