SCHEMBL30239388

SCHEMBL30239388

C[C@H](N)c1cnc2ccccc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.53
PDGFRB P09619 3/20 0.43
PDGFRA P16234 3/20 0.43
MGAM O43451 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42
ALDH1A1 P00352 2/20 0.42
HTR3A P46098 1/20 0.41
CYP2A6 P11509 1/20 0.41
NQO1 P15559 1/20 0.41
AKR1C3 P42330 1/20 0.41
AKR1C2 P52895 1/20 0.41
OGA O60502 1/20 0.41
TLR8 Q9NR97 2/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
BIRC5 O15392 1/20 0.40
GLA P06280 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20023742 1.00 CYP1A2 (0.53) CYP1A2PDGFRBPDGFRAMGAMNPSR1
SCHEMBL1253863 1.00 CYP1A2 (0.53) CYP1A2PDGFRBPDGFRAMGAMNPSR1
SCHEMBL28467592 1.00 CYP1A2 (0.53) CYP1A2PDGFRBPDGFRAMGAMNPSR1
SCHEMBL30447104 1.00 CYP1A2 (0.53) CYP1A2PDGFRBPDGFRAMGAMNPSR1
Hydrochloric Acid SCHEMBL3634472 0.98 CYP1A2 (0.52) CYP1A2PDGFRBPDGFRAMGAMNPSR1
SCHEMBL20030197 0.86 CYP1A2 (0.50) CYP1A2PDGFRBPDGFRAMGAMNPSR1
SCHEMBL2607479 0.85 CYP1A2 (0.57) CYP1A2PDGFRBPDGFRAMGAMNPSR1
SCHEMBL413133 0.83 KDM4E (0.50) CYP1A2MGAMNPSR1ALDH1A1NQO1
Hydrochloric Acid SCHEMBL440306 0.82 ALDH1A1 (0.51) CYP1A2MGAMNPSR1ALDH1A1NQO1
SCHEMBL25085747 0.81 CYP1A2 (0.53) CYP1A2PDGFRBPDGFRAMGAMNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111518166-B Peptidomimetics compound or pharmaceutically acceptable salt thereof, and preparation method and application thereof 中国药科大学 2023-01-31 CN claimed
CN-111518166-B Peptidomimetics compound or pharmaceutically acceptable salt thereof, and preparation method and application thereof 中国药科大学 2023-01-31 CN disclosed