Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 6/20 | 0.46 |
| ▸ | DAO | P14920 | 2/20 | 0.45 |
| ▸ | RHEB | Q15382 | 3/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20839678 | 1.00 | GRIN1 (0.46) | GRIN1NUDT1DAORHEBAXL | |
| SCHEMBL23147720 | 0.87 | NUDT1 (0.46) | NUDT1DAOAXLPRKCICDC7 | |
| SCHEMBL20839895 | 0.85 | NUDT1 (0.61) | NUDT1DAORHEBAXLPRKCI | |
| SCHEMBL30731013 | 0.85 | NUDT1 (0.61) | NUDT1DAORHEBAXLPRKCI | |
| SCHEMBL20839976 | 0.83 | NUDT1 (0.63) | NUDT1DAOAXLPRKCIKMT2A | |
| SCHEMBL899166 | 0.83 | ABL1 (0.45) | NUDT1DAOAXLPRKCI | |
| SCHEMBL30226495 | 0.83 | ABL1 (0.45) | NUDT1DAOAXLPRKCI | |
| SCHEMBL20839846 | 0.81 | NUDT1 (0.64) | NUDT1DAO | |
| SCHEMBL7976646 | 0.81 | DAO (0.45) | NUDT1DAOF7F3IDO1 | |
| SCHEMBL3008612 | 0.80 | IDO1 (0.49) | NUDT1DAORHEBEIF4A3IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118401507-A | Inhibitors targeting ubiquitin-specific protease 7 (USP 7) | 丹娜法伯癌症研究院 | 2024-07-26 | — | — | CN | disclosed |
| EP-4373816-A1 | INHIBITORS TARGETING UBIQUITIN SPECIFIC PROTEASE 7 (USP7) | Dana-Farber Cancer Institute, Inc. (US) | 2024-05-29 | — | — | EP | disclosed |
| WO-2023003973-A1 | INHIBITORS TARGETING UBIQUITIN SPECIFIC PROTEASE 7 (USP7) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-01-26 | — | — | WO | disclosed |