Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20601733 | 1.00 | LRRK2 (0.31) | LRRK2 | |
| SCHEMBL20602586 | 0.88 | NOTUM (0.30) | — | |
| SCHEMBL20602035 | 0.85 | CTSK (0.32) | — | |
| SCHEMBL20599371 | 0.78 | NOTUM (0.30) | — | |
| SCHEMBL20601774 | 0.76 | EGLN2 (0.31) | — | |
| SCHEMBL20602581 | 0.76 | EGLN2 (0.31) | — | |
| SCHEMBL20602570 | 0.75 | — | — | |
| SCHEMBL20601746 | 0.73 | EGLN2 (0.31) | — | |
| SCHEMBL20602060 | 0.72 | EGLN2 (0.30) | — | |
| SCHEMBL20601759 | 0.71 | NOTUM (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3644990-B1 | 5-(PYRIDIN-3-YL)OXAZOLE ALLOSTERIC MODULATORS OF THE M4 MUSCARINIC ACETYLCHOLINE RECEPTOR | MERCK SHARP & DOHME LLC (US) | 2022-11-30 | — | — | EP | disclosed |