Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 8/20 | 0.36 |
| ▸ | ACHE | P22303 | 4/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 3/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24012964 | 0.92 | CYP4F2 (0.41) | KCNA5MAOBACHEMAOACYP4F2 | |
| SCHEMBL30242615 | 0.92 | CYP4F2 (0.41) | KCNA5MAOBACHEMAOACYP4F2 | |
| SCHEMBL26630592 | 0.85 | CYP4F2 (0.39) | PLA2G2AKCNA5ACHECYP4F2CYP4A11 | |
| SCHEMBL24012965 | 0.82 | MAOB (0.41) | KCNA5MAOBACHEMAOACYP4F2 | |
| SCHEMBL24012869 | 0.80 | CYP4F2 (0.37) | CYP4F2CYP4A11 | |
| SCHEMBL24012601 | 0.80 | CYP4F2 (0.37) | CYP4F2CYP4A11 | |
| SCHEMBL24013113 | 0.79 | CYP4F2 (0.52) | MAOBMAOACYP4F2CYP4A11 | |
| SCHEMBL27032051 | 0.78 | CYP4F2 (0.42) | PLA2G2AMAOBACHEMAOACYP4F2 | |
| SCHEMBL27032476 | 0.78 | CYP4F2 (0.40) | PLA2G2AMAOBMAOACYP4F2CYP4A11 | |
| SCHEMBL30242688 | 0.77 | KCNA5 (0.38) | KCNA5MAOBACHEMAOACYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4146658-A1 | NEW MACROCYCLIC LRRK2 KINASE INHIBITORS | Les Laboratoires Servier (FR) | 2023-03-15 | — | — | EP | disclosed |