Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | PRF1 | P14222 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1507192 | 1.00 | GRM5 (0.56) | GRM5MEN1KMT2ASRD5A1AOC3 | |
| SCHEMBL30609592 | 0.86 | DRD2 (0.53) | GRM5MEN1KMT2ADRD2 | |
| SCHEMBL4126390 | 0.84 | SRD5A1 (0.43) | GRM5MEN1KMT2ASRD5A1AOC3 | |
| SCHEMBL4126388 | 0.84 | SRD5A1 (0.43) | GRM5MEN1KMT2ASRD5A1AOC3 | |
| SCHEMBL17519979 | 0.82 | UGCG (0.48) | SRD5A1PRF1 | |
| SCHEMBL18053937 | 0.81 | GRM5 (0.57) | GRM5MEN1KMT2AAOC3PRF1 | |
| SCHEMBL28941260 | 0.81 | HRH3 (0.46) | SRD5A1HRH3DRD2DRD4DRD3 | |
| SCHEMBL424393 | 0.81 | GRM5 (0.57) | GRM5MEN1KMT2ASRD5A1AOC3 | |
| SCHEMBL19699194 | 0.79 | GRM5 (0.56) | GRM5MEN1KMT2ASRD5A1AOC3 | |
| SCHEMBL172065 | 0.79 | GRM5 (0.56) | GRM5MEN1KMT2ASRD5A1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113717156-B | EGFR inhibitor, preparation method and application thereof | 南京红云生物科技有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-115916759-A | Substituted quinazoline compound, preparation method, pharmaceutical composition and application thereof | 南京红云生物科技有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115697996-A | Alkenyl pyrimidine compound, preparation method and application thereof | 南京红云生物科技有限公司 | 2023-02-03 | — | — | CN | disclosed |