Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | IRF3 | Q14653 | 1/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24013078 | 1.00 | BRD4 (0.40) | BRD4L3MBTL1MAPTHTR3AIRF3 | |
| SCHEMBL30242549 | 0.92 | BRD4 (0.38) | BRD4L3MBTL1MAPTHTR3AIRF3 | |
| SCHEMBL24012763 | 0.92 | BRD4 (0.38) | BRD4L3MBTL1MAPTHTR3AIRF3 | |
| SCHEMBL30242683 | 0.90 | FLT1 (0.42) | BRD4STING1PPARG | |
| SCHEMBL26741106 | 0.88 | BRD4 (0.40) | BRD4L3MBTL1MAPTHTR3APDE1B | |
| SCHEMBL30242616 | 0.87 | BRD4 (0.42) | BRD4L3MBTL1MAPTHTR3APDE1B | |
| SCHEMBL24012967 | 0.87 | BRD4 (0.42) | BRD4L3MBTL1MAPTHTR3APDE1B | |
| SCHEMBL24012469 | 0.87 | BRD4 (0.40) | BRD4L3MBTL1MAPTHTR3APDE1B | |
| SCHEMBL30242623 | 0.87 | BRD4 (0.40) | BRD4L3MBTL1MAPTHTR3APDE1B | |
| SCHEMBL24013053 | 0.87 | BRD4 (0.40) | BRD4L3MBTL1MAPTHTR3APDE1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4146658-B1 | NEW MACROCYCLIC LRRK2 KINASE INHIBITORS | ONCODESIGN PREC MEDICINE OPM (FR) | 2025-10-29 | — | — | EP | disclosed |
| EP-4146658-A1 | NEW MACROCYCLIC LRRK2 KINASE INHIBITORS | Les Laboratoires Servier (FR) | 2023-03-15 | — | — | EP | disclosed |