Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.34 |
| ▸ | IRF3 | Q14653 | 1/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24012763 | 1.00 | BRD4 (0.38) | BRD4MAPTL3MBTL1HTR3ACYP1A2 | |
| SCHEMBL24013078 | 0.92 | BRD4 (0.40) | BRD4MAPTL3MBTL1HTR3AIRF3 | |
| SCHEMBL30242573 | 0.92 | BRD4 (0.40) | BRD4MAPTL3MBTL1HTR3AIRF3 | |
| SCHEMBL30242548 | 0.91 | BRD4 (0.38) | BRD4MAPTL3MBTL1HTR3ACYP1A2 | |
| SCHEMBL24012985 | 0.91 | BRD4 (0.38) | BRD4MAPTL3MBTL1HTR3ACYP1A2 | |
| SCHEMBL30242683 | 0.89 | FLT1 (0.42) | BRD4STING1 | |
| SCHEMBL24013053 | 0.85 | BRD4 (0.40) | BRD4MAPTL3MBTL1HTR3ACMKLR1 | |
| SCHEMBL30242740 | 0.85 | BRD4 (0.40) | BRD4MAPTL3MBTL1HTR3ACMKLR1 | |
| SCHEMBL26741106 | 0.85 | BRD4 (0.40) | BRD4MAPTL3MBTL1HTR3APDE1B | |
| SCHEMBL24012967 | 0.85 | BRD4 (0.42) | BRD4MAPTL3MBTL1HTR3APDE1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4146658-A1 | NEW MACROCYCLIC LRRK2 KINASE INHIBITORS | Les Laboratoires Servier (FR) | 2023-03-15 | — | — | EP | disclosed |