Sugi Predict

Sugi Predict / Compounds / SCHEMBL30244593

SCHEMBL30244593

SCHEMBL30244593

CC(C)(C)OC(=O)c1ccc(OCCOCCOCCOCCOCCOCCOCCOCCOCCOc2cc(Cl)cc(NC(=O)NCc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)c2)cc1

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 15/20 0.58
▸ GSPT1 P15170 5/20 0.58
▸ DDB1 Q16531 3/20 0.58
▸ IKZF3 Q9UKT9 1/20 0.58
▸ CYP2C19 P33261 1/20 0.52
▸ KCNH2 Q12809 1/20 0.52
▸ WIZ O95785 3/20 0.43
▸ CSNK1A1 P48729 7/20 0.43
▸ IKZF2 Q9UKS7 5/20 0.41
▸ MAPT P10636 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30244595 1.00 CRBN (0.58) CRBNGSPT1DDB1IKZF3CYP2C19
SCHEMBL30244805 0.91 CRBN (0.60) CRBNGSPT1DDB1IKZF3CYP2C19
SCHEMBL30244665 0.91 CRBN (0.61) CRBNGSPT1DDB1IKZF3CYP2C19
SCHEMBL30244685 0.91 CRBN (0.61) CRBNGSPT1DDB1IKZF3CYP2C19
SCHEMBL30244437 0.89 CRBN (0.58) CRBNGSPT1DDB1IKZF3CYP2C19
SCHEMBL30244584 0.89 CRBN (0.58) CRBNGSPT1DDB1IKZF3CYP2C19
SCHEMBL30244503 0.88 CRBN (0.63) CRBNGSPT1DDB1IKZF3CYP2C19
SCHEMBL30244618 0.88 CRBN (0.63) CRBNGSPT1DDB1IKZF3CYP2C19
SCHEMBL30244629 0.88 CRBN (0.63) CRBNGSPT1DDB1IKZF3CYP2C19
SCHEMBL28881284 0.87 CRBN (0.69) CRBNGSPT1DDB1IKZF3CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022251588-A1 HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE HALDA THERAPEUTICS OPCO, INC. (US) 2022-12-01 — — WO disclosed