Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SLC2A4 | P14672 | 3/20 | 0.39 |
| ▸ | CETP | P11597 | 2/20 | 0.39 |
| ▸ | SLC2A8 | Q9NY64 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30245420 | 0.94 | QPCT (0.44) | QPCTALDH1A1TSHRHRH3MAPK1 | |
| SCHEMBL30245668 | 0.90 | QPCT (0.47) | QPCTTSHRMAPTMAOBCETP | |
| SCHEMBL30245488 | 0.89 | QPCT (0.47) | QPCTMAPK1SLC2A4CETPSLC2A8 | |
| SCHEMBL25258029 | 0.89 | HRH3 (0.45) | QPCTALDH1A1TSHRHRH3MAPT | |
| SCHEMBL30245213 | 0.89 | HRH3 (0.45) | QPCTALDH1A1TSHRHRH3MAPT | |
| SCHEMBL30245279 | 0.88 | QPCT (0.47) | QPCTMAPK1SLC2A4CETPSLC2A8 | |
| SCHEMBL29194586 | 0.88 | QPCT (0.47) | QPCTMAPK1SLC2A4CETPSLC2A8 | |
| SCHEMBL30245717 | 0.88 | QPCT (0.66) | QPCTALDH1A1MAPT | |
| SCHEMBL25424858 | 0.88 | QPCT (0.66) | QPCTALDH1A1MAPT | |
| SCHEMBL25424367 | 0.87 | PTGER2 (0.41) | QPCTALDH1A1TSHRHRH3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4384516-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | Texas Heart Institute (US) | 2024-06-19 | — | — | EP | claimed |
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | claimed |
| WO-2023018472-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-02-16 | — | — | WO | claimed |
| EP-4384516-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | Texas Heart Institute (US) | 2024-06-19 | — | — | EP | disclosed |
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | disclosed |
| WO-2023018472-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-02-16 | — | — | WO | disclosed |