Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | QPCT | Q16769 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP4 | P49662 | 1/20 | 0.36 |
| ▸ | CASP5 | P51878 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30245213 | 1.00 | HRH3 (0.45) | HRH3MAPTHTTQPCTNPC1 | |
| SCHEMBL25251003 | 0.92 | QPCT (0.39) | HRH3MAPTQPCTNPC1ELOVL1 | |
| SCHEMBL30245196 | 0.91 | QPCT (0.39) | HRH3MAPTHTTQPCTNPC1 | |
| SCHEMBL25295796 | 0.91 | QPCT (0.39) | HRH3MAPTHTTQPCTNPC1 | |
| SCHEMBL30245324 | 0.90 | HRH3 (0.50) | HRH3MAPTHTTQPCTNPC1 | |
| SCHEMBL25250533 | 0.90 | HRH3 (0.50) | HRH3MAPTHTTQPCTNPC1 | |
| SCHEMBL30244877 | 0.89 | QPCT (0.49) | HRH3MAPTQPCTALDH1A1TSHR | |
| SCHEMBL25295907 | 0.89 | ALDH1A1 (0.42) | HRH3MAPTNPC1KDM4ELTA4H | |
| SCHEMBL30245019 | 0.89 | ALDH1A1 (0.42) | HRH3MAPTNPC1KDM4ELTA4H | |
| SCHEMBL30245289 | 0.87 | MAPT (0.44) | HRH3MAPTQPCTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | claimed |