Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP4 | P49662 | 1/20 | 0.49 |
| ▸ | CASP5 | P51878 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | CHKA | P35790 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30245540 | 0.96 | KDM4E (0.57) | SIGMAR1KDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL25248944 | 0.96 | KDM4E (0.57) | SIGMAR1KDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL30245608 | 0.95 | KDM4E (0.51) | SIGMAR1KDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL25262872 | 0.95 | KDM4E (0.51) | SIGMAR1KDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL30245251 | 0.94 | KDM4E (0.57) | SIGMAR1KDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL25253290 | 0.94 | SIGMAR1 (0.51) | SIGMAR1KDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL30245515 | 0.94 | SIGMAR1 (0.51) | SIGMAR1KDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL25252729 | 0.93 | SIGMAR1 (0.51) | SIGMAR1KDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL30245166 | 0.93 | SIGMAR1 (0.51) | SIGMAR1KDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL25292297 | 0.92 | KDM4E (0.50) | SIGMAR1KDM4EALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4384516-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | Texas Heart Institute (US) | 2024-06-19 | — | — | EP | claimed |
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | claimed |
| WO-2023018472-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-02-16 | — | — | WO | claimed |
| EP-4384516-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | Texas Heart Institute (US) | 2024-06-19 | — | — | EP | disclosed |
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | disclosed |
| WO-2023018472-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-02-16 | — | — | WO | disclosed |