Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | QPCT | Q16769 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CETP | P11597 | 3/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30245693 | 0.95 | QPCT (0.52) | ALDH1A1QPCTCETPMAPK1MTNR1A | |
| SCHEMBL30245212 | 0.94 | ALDH1A1 (0.47) | ALDH1A1QPCTTSHRCETPHRH3 | |
| SCHEMBL30245310 | 0.94 | QPCT (0.53) | ALDH1A1QPCTCETPMAPK1MTNR1A | |
| SCHEMBL30245218 | 0.93 | ALDH1A1 (0.48) | ALDH1A1QPCTTSHRCETPHRH3 | |
| SCHEMBL25297747 | 0.93 | QPCT (0.47) | ALDH1A1QPCTCETPMTNR1AMTNR1B | |
| SCHEMBL30245285 | 0.93 | QPCT (0.47) | ALDH1A1QPCTCETPMTNR1AMTNR1B | |
| SCHEMBL30245736 | 0.93 | QPCT (0.47) | ALDH1A1QPCTCETPMTNR1AMTNR1B | |
| SCHEMBL30245313 | 0.92 | CETP (0.46) | ALDH1A1QPCTTSHRCETPMTNR1A | |
| SCHEMBL25424604 | 0.92 | CETP (0.46) | ALDH1A1QPCTTSHRCETPMTNR1A | |
| SCHEMBL30245241 | 0.90 | ALDH1A1 (0.46) | ALDH1A1QPCTTSHRCETPHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4384516-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | Texas Heart Institute (US) | 2024-06-19 | — | — | EP | claimed |
| WO-2023018472-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-02-16 | — | — | WO | claimed |
| EP-4384516-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | Texas Heart Institute (US) | 2024-06-19 | — | — | EP | disclosed |
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | disclosed |
| WO-2023018472-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-02-16 | — | — | WO | disclosed |