Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.45 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | AGXT | P21549 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29194663 | 1.00 | POLB (0.46) | POLBAOC3GAASMN1; SMN2HSD17B2 | |
| SCHEMBL30855352 | 0.90 | TAAR1 (0.51) | POLBAOC3GAASMN1; SMN2HSD17B2 | |
| SCHEMBL5311990 | 0.90 | TAAR1 (0.51) | POLBAOC3GAASMN1; SMN2HSD17B2 | |
| SCHEMBL29194742 | 0.86 | CALM1 (0.55) | POLBCALM1CAMKK2TAAR1IDO1 | |
| SCHEMBL25291376 | 0.81 | SLC2A1 (0.44) | POLBAOC3GAASMN1; SMN2HSD17B2 | |
| SCHEMBL30246188 | 0.81 | SLC2A1 (0.44) | POLBAOC3GAASMN1; SMN2HSD17B2 | |
| SCHEMBL30245952 | 0.80 | POLB (0.59) | POLBAOC3GAASMN1; SMN2HSD17B2 | |
| SCHEMBL29194714 | 0.80 | POLB (0.59) | POLBAOC3GAASMN1; SMN2HSD17B2 | |
| SCHEMBL29469439 | 0.79 | HSD17B2 (0.51) | HSD17B2BCHEACHEKMT2AL3MBTL1 | |
| SCHEMBL30854989 | 0.78 | CALM1 (0.55) | AOC3CALM1CAMKK2BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4384516-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | Texas Heart Institute (US) | 2024-06-19 | — | — | EP | disclosed |
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | disclosed |
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | disclosed |
| WO-2023018472-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-02-16 | — | — | WO | disclosed |