Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 2/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | AGXT | P21549 | 2/20 | 0.53 |
| ▸ | CETP | P11597 | 2/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25045945 | 1.00 | QPCT (0.54) | QPCTIDO1AGXTCETPMTNR1A | |
| SCHEMBL30245403 | 0.94 | QPCT (0.52) | QPCTIDO1AGXTCETPMTNR1A | |
| SCHEMBL30245465 | 0.93 | QPCT (0.51) | QPCTIDO1AGXTCETPMTNR1A | |
| SCHEMBL25046128 | 0.90 | QPCT (0.53) | QPCTIDO1AGXTCETPMAOB | |
| SCHEMBL30245847 | 0.90 | QPCT (0.53) | QPCTIDO1AGXTCETPMAOB | |
| SCHEMBL30244988 | 0.89 | QPCT (0.48) | QPCTIDO1AGXTCETPMTNR1A | |
| SCHEMBL30245690 | 0.89 | CETP (0.50) | QPCTIDO1AGXTCETPMTNR1A | |
| SCHEMBL30245930 | 0.88 | QPCT (0.47) | QPCTIDO1AGXTCETPMTNR1A | |
| SCHEMBL30245041 | 0.87 | QPCT (0.49) | QPCTIDO1AGXTCETPMAOB | |
| SCHEMBL30245998 | 0.87 | MAOB (0.60) | QPCTIDO1AGXTCETPMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4384516-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | Texas Heart Institute (US) | 2024-06-19 | — | — | EP | disclosed |
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | disclosed |
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | disclosed |
| WO-2023018472-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-02-16 | — | — | WO | disclosed |