Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.60 |
| ▸ | QPCT | Q16769 | 1/20 | 0.56 |
| ▸ | CETP | P11597 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | AGXT | P21549 | 2/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30245953 | 0.88 | MAOB (0.64) | MAOBQPCTIDO1AGXTSLC2A1 | |
| SCHEMBL30246005 | 0.87 | QPCT (0.54) | MAOBQPCTCETPIDO1AGXT | |
| SCHEMBL25045945 | 0.87 | QPCT (0.54) | MAOBQPCTCETPIDO1AGXT | |
| SCHEMBL30245310 | 0.85 | QPCT (0.53) | MAOBQPCTCETPAPPBCHE | |
| SCHEMBL30245403 | 0.84 | QPCT (0.52) | MAOBQPCTCETPIDO1AGXT | |
| SCHEMBL30245693 | 0.83 | QPCT (0.52) | MAOBQPCTCETPAPPBCHE | |
| SCHEMBL30245041 | 0.83 | QPCT (0.49) | MAOBQPCTCETPIDO1AGXT | |
| SCHEMBL30245465 | 0.83 | QPCT (0.51) | MAOBQPCTCETPIDO1AGXT | |
| SCHEMBL30438881 | 0.83 | CALM1 (0.57) | MAOBQPCTCETPIDO1AGXT | |
| SCHEMBL6678782 | 0.83 | MTNR1A (0.65) | MAOBQPCTCETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4384516-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | Texas Heart Institute (US) | 2024-06-19 | — | — | EP | disclosed |
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | disclosed |
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | disclosed |
| WO-2023018472-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-02-16 | — | — | WO | disclosed |