Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.71 |
| ▸ | GRN | P28799 | 3/20 | 0.50 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1531481 | 0.85 | MAPK1 (0.56) | MAPK1ALDH1A1HPGDALOX15HTT | |
| SCHEMBL1531484 | 0.85 | MAPK1 (0.56) | MAPK1ALDH1A1HPGDALOX15HTT | |
| SCHEMBL3448513 | 0.82 | MAPK1 (0.56) | MAPK1ALDH1A1ALOX15TSHR | |
| SCHEMBL3448516 | 0.82 | MAPK1 (0.56) | MAPK1ALDH1A1ALOX15TSHR | |
| SCHEMBL11198315 | 0.81 | ALDH1A1 (0.57) | MAPK1GRNSORT1ALDH1A1HTT | |
| SCHEMBL11198311 | 0.81 | ALDH1A1 (0.57) | MAPK1GRNSORT1ALDH1A1HTT | |
| SCHEMBL6705695 | 0.81 | GRN (0.62) | MAPK1GRNSORT1ALDH1A1HTT | |
| SCHEMBL6705696 | 0.81 | GRN (0.62) | MAPK1GRNSORT1ALDH1A1HTT | |
| SCHEMBL4448947 | 0.80 | HPGD (0.54) | MAPK1ALDH1A1HPGDALOX15TP53 | |
| SCHEMBL4448945 | 0.80 | HPGD (0.54) | MAPK1ALDH1A1HPGDALOX15TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023055702-A1 | MAIN PROTEASE (M PRO) INHIBITORS AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2023-04-06 | — | — | WO | disclosed |