Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29226904 | 1.00 | BRD4 (0.56) | BRD4L3MBTL1SCN9AITGB3ITGA2B | |
| SCHEMBL29978712 | 0.85 | BRD4 (0.57) | BRD4L3MBTL1SCN9AITGB3ITGA2B | |
| SCHEMBL758149 | 0.85 | BRD4 (0.57) | BRD4L3MBTL1SCN9AITGB3ITGA2B | |
| SCHEMBL18497019 | 0.84 | BRD4 (0.58) | BRD4L3MBTL1SCN9AITGB3ITGA2B | |
| SCHEMBL19030483 | 0.83 | BRD4 (0.57) | BRD4L3MBTL1SCN9AITGB3ITGA2B | |
| SCHEMBL29227030 | 0.82 | ITGB3 (0.54) | BRD4L3MBTL1SCN9AITGB3ITGA2B | |
| SCHEMBL29227346 | 0.81 | ITGB3 (0.56) | BRD4L3MBTL1SCN9AITGB3ITGA2B | |
| SCHEMBL23768797 | 0.81 | BRD4 (0.58) | BRD4L3MBTL1SCN9AITGB3ITGA2B | |
| SCHEMBL5914780 | 0.81 | BRD4 (0.55) | BRD4L3MBTL1SCN9AITGB3ITGA2B | |
| SCHEMBL29979065 | 0.81 | BRD4 (0.55) | BRD4L3MBTL1SCN9AITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4384268-A1 | SMALL MOLECULE UREA DERIVATIVES AS STING ANTAGONISTS | Curadev Pharma Pvt. Ltd. (IN) | 2024-06-19 | — | — | EP | disclosed |
| CN-118019738-A | Small molecule urea derivatives as STING antagonists | 库拉德夫制药私人有限公司 | 2024-05-10 | — | — | CN | disclosed |
| WO-2023017452-A1 | SMALL MOLECULE UREA DERIVATIVES AS STING ANTAGONISTS | CURADEV PHARMA PVT. LTD. (IN) | 2023-02-16 | — | — | WO | disclosed |