Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 17/20 | 0.35 |
| ▸ | TAF1 | P21675 | 3/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | PLK1 | P53350 | 4/20 | 0.33 |
| ▸ | BRDT | Q58F21 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30248840 | 0.84 | PLK1 (0.42) | BRD4TAF1PARP1PLK1 | |
| SCHEMBL30249002 | 0.84 | PLK1 (0.42) | BRD4TAF1PARP1PLK1 | |
| SCHEMBL31315968 | 0.74 | NOS3 (0.32) | NOS3NOS1NOS2 | |
| SCHEMBL31315956 | 0.73 | PNP (0.33) | NOS3NOS1NOS2 | |
| SCHEMBL12958940 | 0.65 | PNP (0.36) | NOS3NOS1NOS2 | |
| SCHEMBL15826586 | 0.65 | BRD4 (0.51) | BRD4TAF1 | |
| SCHEMBL21261421 | 0.65 | BRD4 (0.41) | BRD4 | |
| SCHEMBL21261459 | 0.65 | BRD4 (0.51) | BRD4TAF1 | |
| SCHEMBL18261934 | 0.65 | BRD4 (0.51) | BRD4TAF1 | |
| SCHEMBL17841062 | 0.65 | BRD4 (0.51) | BRD4TAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016134-A1 | COMPOUND CONTAINING TETRAHYDROPTERIN STRUCTURE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国药科大学 | 2023-02-16 | — | — | WO | disclosed |