Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAT1 | P18440 | 5/20 | 0.74 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.69 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.62 |
| ▸ | GSK3B | P49841 | 2/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.59 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | MMP3 | P08254 | 1/20 | 0.57 |
| ▸ | MMP13 | P45452 | 1/20 | 0.57 |
| ▸ | PIM1 | P11309 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MYC | P01106 | 1/20 | 0.53 |
| ▸ | MAX | P61244 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18102890 | 0.89 | NAT1 (0.76) | NAT1ADAMTS5CISD1GSK3BCA2 | |
| SCHEMBL18102962 | 0.89 | NAT1 (0.76) | NAT1ADAMTS5CISD1GSK3BCA2 | |
| SCHEMBL19991267 | 0.89 | NAT1 (0.76) | NAT1ADAMTS5CISD1GSK3BCA2 | |
| SCHEMBL18103002 | 0.87 | NAT1 (0.74) | NAT1ADAMTS5CISD1CA2EPHX1 | |
| SCHEMBL8312114 | 0.86 | ADAMTS5 (0.75) | NAT1ADAMTS5CISD1MMP3MMP13 | |
| SCHEMBL7557614 | 0.85 | NAT1 (1.00) | NAT1ADAMTS5CISD1GSK3BCA2 | |
| SCHEMBL7557609 | 0.85 | NAT1 (1.00) | NAT1ADAMTS5CISD1GSK3BCA2 | |
| SCHEMBL18103005 | 0.83 | NAT1 (0.85) | NAT1ADAMTS5CISD1CA2EPHX1 | |
| SCHEMBL8167436 | 0.82 | PIM1 (0.75) | NAT1CISD1CA2EPHX1CRHBP | |
| SCHEMBL8167434 | 0.82 | PIM1 (0.75) | NAT1CISD1CA2EPHX1CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023039170-A1 | SELECTIVE TARGETING OF CD38 ACTIVITY AS AN IMMUNOSTIMULATORY AND ANTITUMOR STRATEGY | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2023-03-16 | — | — | WO | disclosed |