Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.92 |
| ▸ | CLK1 | P49759 | 1/20 | 0.92 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.92 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.92 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.92 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.92 |
| ▸ | PIM1 | P11309 | 2/20 | 0.71 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.71 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
| ▸ | NAT1 | P18440 | 4/20 | 0.70 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.65 |
| ▸ | MMP3 | P08254 | 1/20 | 0.65 |
| ▸ | MMP13 | P45452 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15421331 | 0.96 | CSNK2A2 (1.00) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL8312399 | 0.96 | CSNK2A2 (1.00) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL8312402 | 0.96 | CSNK2A2 (1.00) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL18103036 | 0.87 | MEN1 (0.71) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL8312114 | 0.87 | ADAMTS5 (0.75) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL4050762 | 0.85 | HPGD (0.82) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL4050763 | 0.85 | HPGD (0.82) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL1247708 | 0.84 | PIM1 (1.00) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL1247705 | 0.84 | PIM1 (1.00) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL2546911 | 0.84 | PIM1 (1.00) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023039170-A1 | SELECTIVE TARGETING OF CD38 ACTIVITY AS AN IMMUNOSTIMULATORY AND ANTITUMOR STRATEGY | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2023-03-16 | — | — | WO | disclosed |