Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30250581 | 0.90 | RIPK1 (0.47) | RIPK1 | |
| SCHEMBL30250600 | 0.87 | RIPK1 (0.59) | RIPK1 | |
| SCHEMBL30250714 | 0.87 | RIPK1 (0.56) | RIPK1 | |
| SCHEMBL21531284 | 0.85 | RIPK1 (0.63) | RIPK1 | |
| SCHEMBL21531281 | 0.85 | RIPK1 (0.63) | RIPK1 | |
| SCHEMBL21531040 | 0.84 | RIPK1 (0.47) | RIPK1 | |
| SCHEMBL21531041 | 0.84 | RIPK1 (0.47) | RIPK1 | |
| SCHEMBL30250592 | 0.83 | RIPK1 (0.53) | RIPK1 | |
| SCHEMBL23075443 | 0.82 | RIPK1 (0.63) | RIPK1 | |
| SCHEMBL30157019 | 0.81 | RIPK1 (0.42) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023020486-A1 | RIP1 KINASE INHIBITOR COMPOUND AND COMPOSITION AND USE THEREOF | 广州市恒诺康医药科技有限公司 | 2023-02-23 | — | — | WO | disclosed |