Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | DAO | P14920 | 2/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | P4HA1 | P13674 | 3/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23858342 | 1.00 | KDM4E (0.54) | KDM4ENPC1RAB9AHKDC1TDP1 | |
| SCHEMBL21061877 | 0.84 | NPC1 (0.41) | KDM4ENPC1RAB9AHKDC1TDP1 | |
| SCHEMBL31003177 | 0.84 | NPC1 (0.41) | KDM4ENPC1RAB9AHKDC1TDP1 | |
| SCHEMBL23350442 | 0.80 | MAPK1 (0.44) | KDM4ENPC1RAB9AHKDC1TDP1 | |
| SCHEMBL21958562 | 0.72 | DAO (0.32) | KDM4ENPC1RAB9AHKDC1TDP1 | |
| SCHEMBL31292233 | 0.71 | DAO (0.38) | KDM4ENPC1RAB9AHKDC1TDP1 | |
| SCHEMBL4715955 | 0.70 | KDM4E (0.50) | KDM4ENPC1RAB9AHKDC1TDP1 | |
| SCHEMBL192332 | 0.70 | NPC1 (1.00) | KDM4ENPC1RAB9AHKDC1TDP1 | |
| SCHEMBL21061964 | 0.70 | KDM4E (0.58) | KDM4ENPC1RAB9AHKDC1TDP1 | |
| SCHEMBL20031275 | 0.70 | NPC1 (0.53) | KDM4ENPC1RAB9AMGAMHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335378-B | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2025-03-04 | — | — | CN | disclosed |
| EP-4126860-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | Janssen Pharmaceutica NV (BE) | 2023-02-08 | — | — | EP | disclosed |