Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ASPH | Q12797 | 2/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | AGER | Q15109 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3439334 | 1.00 | KDM4E (0.39) | KDM4EASPHKDM8ALDH1A1POLB | |
| SCHEMBL17873823 | 0.75 | ADORA2A (0.37) | ALDH1A1GAAMAPTHCRTR2HCRTR1 | |
| SCHEMBL12384969 | 0.73 | ALDH1A1 (0.33) | KDM4EALDH1A1POLBGAAAPOBEC3A | |
| SCHEMBL19736277 | 0.73 | RXFP1 (0.47) | KDM4EALDH1A1POLBCYP3A4MAPT | |
| SCHEMBL567752 | 0.73 | CCR1 (0.54) | CYP3A4 | |
| SCHEMBL14980128 | 0.73 | CYP2A6 (0.39) | ALDH1A1 | |
| SCHEMBL23858559 | 0.72 | KDM4E (0.43) | KDM4EALDH1A1POLBMAPTKDR | |
| SCHEMBL30886184 | 0.72 | PI4KA (0.50) | KDM4EALDH1A1MAPTTSHR | |
| SCHEMBL30295640 | 0.72 | RXFP1 (0.41) | ALDH1A1CYP3A4MAPT | |
| SCHEMBL17873835 | 0.72 | RXFP1 (0.41) | ALDH1A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335378-B | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2025-03-04 | — | — | CN | disclosed |
| EP-4126860-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | Janssen Pharmaceutica NV (BE) | 2023-02-08 | — | — | EP | disclosed |