Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | ATM | Q13315 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | CDC25B | P30305 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | FADS1 | O60427 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13367372 | 0.87 | ALDH1A1 (0.71) | ALDH1A1HPGDATMHSD17B10TP53 | |
| SCHEMBL31440468 | 0.87 | ALDH1A1 (0.71) | ALDH1A1HPGDATMHSD17B10TP53 | |
| SCHEMBL30252352 | 0.86 | ALDH1A1 (0.51) | ALDH1A1HPGDATMHSD17B10TP53 | |
| SCHEMBL29165721 | 0.82 | TRPV1 (0.55) | ALDH1A1HPGDATMHSD17B10TP53 | |
| SCHEMBL30252321 | 0.82 | TRPV1 (0.55) | ALDH1A1HPGDATMHSD17B10TP53 | |
| SCHEMBL30252623 | 0.82 | MEN1 (0.55) | ALDH1A1HPGDATMHSD17B10TP53 | |
| SCHEMBL29350230 | 0.82 | ALDH1A1 (1.00) | ALDH1A1HPGDATMHSD17B10TP53 | |
| SCHEMBL19796 | 0.82 | ALDH1A1 (1.00) | ALDH1A1HPGDATMHSD17B10TP53 | |
| SCHEMBL22925205 | 0.81 | CDC25B (0.69) | ALDH1A1HPGDATMHSD17B10TP53 | |
| SCHEMBL349530 | 0.81 | ALDH1A1 (0.50) | ALDH1A1HPGDATMHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115947755-B | Synthesis method of biaryl aniline axial chiral derivative | 泽升科技(广州)有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-115947755-A | Synthetic method of biarylaniline axial chiral derivative | 泽升科技(广州)有限公司 | 2023-04-11 | — | — | CN | disclosed |