Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23857243 | 1.00 | PPIA (0.31) | PPIAP2RX7ACACBACACA | |
| SCHEMBL23857546 | 0.86 | PPIA (0.33) | PPIAP2RX7 | |
| SCHEMBL30047510 | 0.86 | PPIA (0.31) | PPIAP2RX7 | |
| SCHEMBL23856570 | 0.86 | PPIA (0.31) | PPIAP2RX7 | |
| SCHEMBL30253411 | 0.86 | PPIA (0.33) | PPIAP2RX7 | |
| SCHEMBL23857385 | 0.81 | STK17B (0.39) | ACACBACACA | |
| SCHEMBL30253173 | 0.81 | STK17B (0.39) | ACACBACACA | |
| SCHEMBL28908791 | 0.78 | P2RX7 (0.35) | PPIAP2RX7ACACB | |
| SCHEMBL23857192 | 0.77 | AAK1 (0.32) | — | |
| SCHEMBL30047724 | 0.77 | AAK1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4126855-A1 | COMPOUNDS AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTION | F. Hoffmann-La Roche AG (CH) | 2023-02-08 | — | — | EP | disclosed |