Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.41 |
| ▸ | MOK | Q9UQ07 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 7/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | MAP4K1 | Q92918 | 4/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30253096 | 0.82 | MAP4K1 (0.42) | F10CYP11B2MAP4K1PIK3CA | |
| SCHEMBL30253186 | 0.73 | MTOR (0.48) | F10JAK2JAK1TYK2JAK3 | |
| SCHEMBL30252926 | 0.73 | PTK2 (0.43) | JAK2TYK2 | |
| SCHEMBL24157096 | 0.71 | TYK2 (0.46) | F10JAK2JAK1TYK2JAK3 | |
| SCHEMBL30369246 | 0.71 | TYK2 (0.46) | F10JAK2JAK1TYK2JAK3 | |
| SCHEMBL30369639 | 0.70 | F10 (0.44) | F10JAK2JAK1TYK2JAK3 | |
| SCHEMBL24156727 | 0.70 | F10 (0.44) | F10JAK2JAK1TYK2JAK3 | |
| SCHEMBL23768205 | 0.70 | TYK2 (0.46) | F10JAK2JAK1TYK2JAK3 | |
| SCHEMBL27083573 | 0.69 | TYK2 (0.44) | F10JAK2JAK1TYK2JAK3 | |
| SCHEMBL24156174 | 0.69 | TYK2 (0.41) | F10JAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115715288-A | TYK-2 inhibitors | 百济神州有限公司 | 2023-02-24 | — | — | CN | disclosed |