Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.41 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23857362 | 1.00 | GRM2 (0.41) | GRM2GRM3AKR1B1ADRA2AADRA2B | |
| SCHEMBL4599994 | 0.86 | GRM2 (0.39) | GRM2GRM3AKR1B1ADRA2AADRA2B | |
| SCHEMBL8828732 | 0.86 | ADRA2A (0.46) | GRM2GRM3AKR1B1ADRA2AADRA2B | |
| SCHEMBL23857218 | 0.81 | HDAC11 (0.36) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL27775131 | 0.80 | HTR2A (0.35) | GRM2GRM3ADRA2AADRA2BADRA2C | |
| SCHEMBL3304544 | 0.78 | BRD4 (0.40) | ADRA1AKDM4EALDH1A1CYP1A2TSHR | |
| SCHEMBL29476532 | 0.78 | HDAC9 (0.44) | GRM2 | |
| SCHEMBL122942 | 0.78 | HDAC9 (0.44) | GRM2 | |
| SCHEMBL23857123 | 0.76 | AKR1B1 (0.42) | GRM2GRM3AKR1B1ADRA2AADRA2B | |
| SCHEMBL8649961 | 0.76 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4126855-A1 | COMPOUNDS AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTION | F. Hoffmann-La Roche AG (CH) | 2023-02-08 | — | — | EP | disclosed |