Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 2/20 | 0.35 |
| ▸ | PAK1 | Q13153 | 3/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA4 | P22748 | 3/20 | 0.33 |
| ▸ | CA7 | P43166 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CKS1B | P61024 | 2/20 | 0.33 |
| ▸ | SKP1 | P63208 | 2/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.33 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.33 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30255236 | 0.87 | CKS1B (0.35) | PAK1OPRK1CKS1BSKP1SKP2 | |
| SCHEMBL20500375 | 0.84 | CKS1B (0.46) | BTKOPRK1CKS1BSKP1SKP2 | |
| SCHEMBL30254917 | 0.83 | OPRK1 (0.36) | KDM4EOPRK1CKS1BSKP1SKP2 | |
| SCHEMBL20500383 | 0.82 | TSHR (0.47) | — | |
| SCHEMBL28347956 | 0.79 | KDM4E (0.33) | KDM4EHSD17B10CKS1BSKP1SKP2 | |
| SCHEMBL16694846 | 0.78 | CYP3A4 (0.39) | PAK1OPRK1CKS1BSKP1SKP2 | |
| SCHEMBL20500351 | 0.74 | CKS1B (0.47) | BTKOPRK1CKS1BSKP1SKP2 | |
| SCHEMBL21248810 | 0.73 | SMPD3 (0.35) | BTKOPRK1CA12CA1CA2 | |
| SCHEMBL21248811 | 0.73 | SMPD3 (0.35) | BTKOPRK1CA12CA1CA2 | |
| SCHEMBL21810274 | 0.72 | CHEK1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110650951-B | Somatostatin modulators and uses thereof | 克林提克斯医药股份有限公司 | 2023-02-24 | — | — | CN | disclosed |