Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 20/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 2/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.76 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.76 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.76 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16774171 | 1.00 | ADORA3 (1.00) | ADORA3KCNH2SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL20122183 | 1.00 | ADORA3 (1.00) | ADORA3KCNH2SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL18352432 | 0.93 | ADORA3 (0.86) | ADORA3KCNH2SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL30255447 | 0.88 | ADORA3 (1.00) | ADORA3 | |
| SCHEMBL16774178 | 0.88 | ADORA3 (1.00) | ADORA3 | |
| SCHEMBL20122173 | 0.88 | ADORA3 (1.00) | ADORA3 | |
| SCHEMBL21758636 | 0.87 | ADORA3 (1.00) | ADORA3KCNH2 | |
| SCHEMBL20122111 | 0.87 | ADORA3 (1.00) | ADORA3KCNH2 | |
| SCHEMBL16774182 | 0.87 | ADORA3 (1.00) | ADORA3KCNH2 | |
| SCHEMBL10323827 | 0.87 | ADORA3 (1.00) | ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003212-B | A3 adenosine receptor agonists | 美国卫生和人力服务部 | 2022-12-06 | — | — | CN | disclosed |