SCHEMBL30255461

SCHEMBL30255461

Clc1nc(-c2cccc3oc4ccccc4c23)c2ccccc2n1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.47
ALDH1A1 P00352 2/20 0.47
ADORA2A P29274 3/20 0.39
C1R P00736 1/20 0.38
CYP1A2 P05177 1/20 0.38
MAPT P10636 2/20 0.38
USP2 O75604 1/20 0.38
HPGD P15428 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
MEN1 O00255 1/20 0.37
MITF O75030 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18455537 1.00 KDM4E (0.47) KDM4EALDH1A1ADORA2AC1RCYP1A2
SCHEMBL31195697 0.89 KDM4E (0.56) KDM4EALDH1A1ADORA2AMAPTHPGD
SCHEMBL23610016 0.88 KDM4E (0.42) KDM4EALDH1A1ADORA2AC1RCYP1A2
SCHEMBL22893675 0.87 KDM4E (0.46) KDM4EALDH1A1ADORA2AC1RMAPT
SCHEMBL14233141 0.84 KDM4E (0.46) KDM4EALDH1A1ADORA2AC1RMAPT
SCHEMBL23609708 0.84 KDM4E (0.41) KDM4EALDH1A1ADORA2AC1RCYP1A2
SCHEMBL23112270 0.83 TDP1 (0.41) KDM4EALDH1A1CYP1A2MAPTHPGD
SCHEMBL22697721 0.83 KDM4E (0.40) KDM4EALDH1A1ADORA2AC1RMAPT
SCHEMBL22698060 0.83 KDM4E (0.44) KDM4EALDH1A1ADORA2AC1RMAPT
SCHEMBL17524694 0.82 ALDH1A1 (0.43) KDM4EALDH1A1ADORA2ACYP1A2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118852194-A Organic electroluminescent compound and application thereof 宁波卢米蓝新材料有限公司 2024-10-29 CN disclosed
CN-118406034-A Organic electroluminescent compound and organic electroluminescent device comprising the same 罗门哈斯电子材料韩国有限公司 2024-07-30 CN disclosed
CN-112341447-B Electron transport material, organic electroluminescent device and display device 烟台京师材料基因组工程研究院 2022-12-06 CN disclosed