Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 6/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | PTH1R | Q03431 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.30 |
| ▸ | MERTK | Q12866 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25202242 | 1.00 | NR3C1 (0.33) | NR3C1CYP19A1CYP11B1CYP11B2FEN1 | |
| SCHEMBL25267103 | 1.00 | NR3C1 (0.33) | NR3C1CYP19A1CYP11B1CYP11B2FEN1 | |
| SCHEMBL25554251 | 0.97 | FEN1 (0.35) | NR3C1CYP19A1CYP11B1CYP11B2FEN1 | |
| SCHEMBL30256925 | 0.97 | FEN1 (0.35) | NR3C1CYP19A1CYP11B1CYP11B2FEN1 | |
| SCHEMBL30257336 | 0.91 | AXL (0.32) | NR3C1FEN1ALOX5APPTH1RGRM5 | |
| SCHEMBL25556047 | 0.91 | AXL (0.32) | NR3C1FEN1ALOX5APPTH1RGRM5 | |
| SCHEMBL25556046 | 0.91 | AXL (0.32) | NR3C1FEN1ALOX5APPTH1RGRM5 | |
| SCHEMBL30257072 | 0.90 | KDM1A (0.35) | NR3C1CYP19A1CYP11B1CYP11B2FEN1 | |
| SCHEMBL30256980 | 0.90 | KDM1A (0.35) | NR3C1CYP19A1CYP11B1CYP11B2FEN1 | |
| SCHEMBL25554426 | 0.90 | KDM1A (0.35) | NR3C1CYP19A1CYP11B1CYP11B2FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4137481-A1 | ARYL OR HETEROARYL DERIVATIVE | Teijin Pharma Limited (JP) | 2023-02-22 | — | — | EP | disclosed |