Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 7/20 | 0.35 |
| ▸ | NSD2 | O96028 | 4/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.32 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25554854 | 1.00 | CRHR1 (0.35) | CRHR1NSD2SCN9ALOXL2ADORA2A | |
| SCHEMBL30257220 | 0.93 | CRHR1 (0.34) | CRHR1SCN9AADORA2AADORA1SLC2A1 | |
| SCHEMBL25554461 | 0.93 | CRHR1 (0.34) | CRHR1SCN9AADORA2AADORA1SLC2A1 | |
| SCHEMBL25554810 | 0.88 | CRHR1 (0.33) | CRHR1SCN9AADORA2AADORA1SLC2A1 | |
| SCHEMBL25555463 | 0.86 | NSD2 (0.33) | NSD2SCN9ACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL25555468 | 0.86 | NSD2 (0.33) | NSD2SCN9A | |
| SCHEMBL25555465 | 0.86 | NSD2 (0.33) | NSD2SCN9A | |
| SCHEMBL30256868 | 0.85 | CRHR1 (0.33) | CRHR1NSD2SCN9ASLC2A1SLC2A3 | |
| SCHEMBL25554458 | 0.85 | CRHR1 (0.33) | CRHR1NSD2SCN9ASLC2A1SLC2A3 | |
| SCHEMBL25057937 | 0.85 | GRM5 (0.37) | NSD2CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | claimed |
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | disclosed |
| EP-4137481-A1 | ARYL OR HETEROARYL DERIVATIVE | Teijin Pharma Limited (JP) | 2023-02-22 | — | — | EP | disclosed |