SCHEMBL30257576

SCHEMBL30257576

Clc1ccc2c3ccccc3n(-c3ccc(-c4ccccc4)c(-c4ccccc4)c3)c2c1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.43
ATM Q13315 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
MAT2A P31153 13/20 0.40
MAPK8 P45983 1/20 0.39
MAPK9 P45984 1/20 0.39
MAPK14 Q16539 1/20 0.38
PRMT5 O14744 2/20 0.38
MDM2 Q00987 1/20 0.37
CYP1A2 P05177 2/20 0.37
METAP2 P50579 1/20 0.37
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
MAT1A Q00266 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30997590 0.94 KDM4E (0.41) KDM4EATML3MBTL1MAT2AMAPK8
SCHEMBL24947187 0.91 KDM4E (0.46) KDM4EATML3MBTL1MAPK14MDM2
SCHEMBL24949540 0.91 KDM4E (0.46) KDM4EATML3MBTL1MAPK14MDM2
SCHEMBL29892663 0.90 L3MBTL1 (0.49) KDM4EATML3MBTL1MAT2AMAPK8
SCHEMBL26148648 0.88 L3MBTL1 (0.50) KDM4EATML3MBTL1MAT2AMAPK14
SCHEMBL25988905 0.87 L3MBTL1 (0.42) KDM4EATML3MBTL1MAT2AMAPK8
SCHEMBL24948312 0.86 KDM4E (0.47) KDM4EATML3MBTL1MAT2AMAPK14
SCHEMBL24947196 0.86 KDM4E (0.47) KDM4EATML3MBTL1MAT2AMAPK14
SCHEMBL24949671 0.85 KDM4E (0.38) KDM4EATML3MBTL1MDM2CYP1A2
SCHEMBL24948417 0.85 KDM4E (0.38) KDM4EATML3MBTL1MDM2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023013615-A1 AMINE COMPOUND, HOLE INJECTION LAYER AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2023-02-09 WO disclosed