Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 4/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30258619 | 0.84 | DRD2 (0.35) | CRBNDDB1DRD2SLC6A4 | |
| SCHEMBL22835720 | 0.84 | CRBN (0.41) | CRBNDDB1MAPK14DRD2SLC6A4 | |
| SCHEMBL22835628 | 0.84 | PDE4B (0.42) | CRBNDDB1 | |
| Hydrochloric Acid SCHEMBL30258093 | 0.83 | CRBN (0.40) | CRBNDDB1MAPK14DRD2SLC6A4 | |
| SCHEMBL30258214 | 0.83 | DRD2 (0.38) | CRBNDDB1DRD2SLC6A4 | |
| SCHEMBL25448761 | 0.82 | CRBN (0.58) | CRBNDDB1 | |
| Hydrochloric Acid SCHEMBL30258751 | 0.82 | DRD2 (0.37) | CRBNDDB1DRD2SLC6A4 | |
| SCHEMBL23842383 | 0.76 | CRBN (0.42) | CRBNDDB1DRD2SLC6A4 | |
| SCHEMBL30733899 | 0.73 | DDB1 (0.50) | CRBNDDB1 | |
| SCHEMBL26855554 | 0.71 | CRBN (0.63) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023059792-A1 | CORONAVIRUS NON-STRUCTURAL PROTEIN 3 DEGRADING COMPOUNDS | C4 THRAPEUTICS, INC. (US) | 2023-04-13 | — | — | WO | disclosed |