⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10730903 | 0.77 | — | — | |
| SCHEMBL14850640 | 0.77 | — | — | |
| SCHEMBL69879 | 0.69 | — | — | |
| SCHEMBL5510095 | 0.67 | — | — | |
| SCHEMBL19078880 | 0.67 | MAPT (0.34) | — | |
| SCHEMBL2822503 | 0.66 | LMNA (0.42) | — | |
| SCHEMBL3108431 | 0.65 | — | — | |
| SCHEMBL6727620 | 0.65 | — | — | |
| SCHEMBL5028263 | 0.65 | — | — | |
| SCHEMBL13909523 | 0.64 | MAPT (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11091443-B2 | Flexible piezoelectric and ferroelectric haloimidazole crystals | NORTHWESTERN UNIVERSITY (US) | 2021-08-17 | — | — | US | claimed |
| US-20190127331-A1 | FLEXIBLE PIEZOELECTRIC AND FERROELECTRIC HALOIMIDAZOLE CRYSTALS | NORTHWESTERN UNIVERSITY (US) | 2019-05-02 | — | — | US | claimed |
| CN-109643752-A | FLEXIBLE PIEZOELECTRIC AND FERROELECTRIC HALOIMIDAZOLE CRYSTALS | 西北大学 | 2019-04-16 | — | — | CN | claimed |
| EP-3443601-A1 | FLEXIBLE PIEZOELECTRIC AND FERROELECTRIC HALOIMIDAZOLE CRYSTALS | Northwestern University (US) | 2019-02-20 | — | — | EP | claimed |
| WO-2017180721-A1 | FLEXIBLE PIEZOELECTRIC AND FERROELECTRIC HALOIMIDAZOLE CRYSTALS | NORTHWESTERN UNIVERSITY (US) | 2017-10-19 | — | — | WO | claimed |
| US-11091443-B2 | Flexible piezoelectric and ferroelectric haloimidazole crystals | NORTHWESTERN UNIVERSITY (US) | 2021-08-17 | — | — | US | disclosed |
| US-11021444-B2 | Antiviral compounds | Janssen Biopharma, Inc. (US) | 2021-06-01 | — | — | US | disclosed |
| US-20190263754-A1 | ANTIVIRAL COMPOUNDS | ALIOS BIOPHARMA, INC. (US) | 2019-08-29 | — | — | US | disclosed |
| US-20190127331-A1 | FLEXIBLE PIEZOELECTRIC AND FERROELECTRIC HALOIMIDAZOLE CRYSTALS | NORTHWESTERN UNIVERSITY (US) | 2019-05-02 | — | — | US | disclosed |
| CN-109643752-A | FLEXIBLE PIEZOELECTRIC AND FERROELECTRIC HALOIMIDAZOLE CRYSTALS | 西北大学 | 2019-04-16 | — | — | CN | disclosed |
| EP-3443601-A1 | FLEXIBLE PIEZOELECTRIC AND FERROELECTRIC HALOIMIDAZOLE CRYSTALS | Northwestern University (US) | 2019-02-20 | — | — | EP | disclosed |
| US-10174052-B2 | Quinuclidine compounds as α-7 nicotinic acetylcholine receptor ligands | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-01-08 | — | — | US | disclosed |
| US-8076324-B2 | Di(hetero)arylcyclohexane derivatives, their preparation, their use and pharmaceutical compositions comprising them | SANOFI-AVENTIS (FR) | 2011-12-13 | — | — | US | disclosed |
| US-20100204206-A1 | Di(hetero)arylcyclohexane derivatives, their preparation, their use and pharmaceutical compositions comprising them | SANOFI-AVENTIS (FR) | 2010-08-12 | — | — | US | disclosed |
| EP-2164825-A1 | DI(HETERO)ARYLCYCLOHEXANE DERIVATIVES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | Sanofi-Aventis (FR) | 2010-03-24 | — | — | EP | disclosed |
| EP-2141151-A1 | METHOD FOR PRODUCING 2-HALOIMIDAZOLE COMPOUND | SHIKOKU CHEMICALS CORPORATION (JP) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008148468-A1 | DI(HETERO)ARYLCYCLOHEXANE DERIVATIVES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | SANOFI-AVENTIS (FR) | 2008-12-11 | — | — | WO | disclosed |
| US-20030040630-A1 | Method for producing sulfonyl imidazole derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2003-02-27 | — | — | US | disclosed |
| EP-1265902-A1 | METHOD FOR PRODUCING SULFONYL IMIDAZOLE DERIVATIVES BY PHASE TRANSFER CATALYSIS | Bayer CropScience AG (DE) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001057043-A1 | METHOD FOR PRODUCING SULFONYL IMIDAZOLE DERIVATIVES BY PHASE TRANSFER CATALYSIS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-09 | — | — | WO | disclosed |