Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | NR2E3 | Q9Y5X4 | 2/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561323 | 0.88 | TSHR (0.41) | TSHRALDH1A1EPHX2TDP1MAPT | |
| SCHEMBL11694216 | 0.86 | TSHR (0.54) | TSHRLMNAALDH1A1KDM5AKDM7A | |
| SCHEMBL11695325 | 0.86 | TSHR (0.54) | TSHRLMNAALDH1A1KDM5AKDM7A | |
| SCHEMBL11858995 | 0.86 | TSHR (0.54) | TSHRLMNAALDH1A1KDM5AKDM7A | |
| SCHEMBL11692421 | 0.86 | TSHR (0.54) | TSHRLMNAALDH1A1KDM5AKDM7A | |
| SCHEMBL11695993 | 0.86 | TSHR (0.54) | TSHRLMNAALDH1A1KDM5AKDM7A | |
| SCHEMBL7747296 | 0.84 | TSHR (0.38) | TSHRALDH1A1EPHX2TDP1MAPT | |
| SCHEMBL7747291 | 0.84 | TSHR (0.38) | TSHRALDH1A1EPHX2TDP1MAPT | |
| SCHEMBL7747301 | 0.84 | TSHR (0.38) | TSHRALDH1A1EPHX2TDP1MAPT | |
| SCHEMBL31520116 | 0.83 | EPHX2 (0.40) | ALDH1A1KDM5AKDM7AKDM4CPHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023059792-A1 | CORONAVIRUS NON-STRUCTURAL PROTEIN 3 DEGRADING COMPOUNDS | C4 THRAPEUTICS, INC. (US) | 2023-04-13 | — | — | WO | disclosed |